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师资队伍

Chengzhi He

 

Email: czhe@mail.buct.edu.cn

Phone: +86-13370154991

Wechat: heorange

Office Location:

Computer Building West 306

Chengzhi He

Professor, Full-time Principal Investigator

 

Education:

Ph. D., Chemistry, 2016, The University of British Columbia, Canada

B. S., Chemistry, 2009, Jilin University, China

 

Specializations: Biophysics, biomaterials

 

Research focuses:

Mechanobiology
Single-molecule force spectroscopy
Protein-protein/ligand interaction
Protein folding/unfolding
Protein-based materials

Publications:

• He CZ, Genchev GZ, Lu H, Li HB*. Mechanically Untying a Protein Slipknot: Multiple Pathways Revealed by Force Spectroscopy and Steered Molecular Dynamics Simulations. J. Am. Chem. Soc., 2012, 134 (25), pp 10428.

• He CZ, Lamour G, Xiao A, Gsponer J, Li HB*. Mechanically Tightening a Protein Slipknot into a Trefoil Knot. J. Am. Chem. Soc., 2014, 136 (34), pp 11946.

• He CZ, Hu CG, Hu XD, Hu XT, Xiao A, Perkins, TT, Li HB* Directly Observing the Reversible Unfolding and Refolding of an α/β Protein by Single-Molecule Atomic Force Microscopy. Angew. Chem. Int. Ed., 2015, 127(34), 10059-10063.

He CZ, Li HB*, Staphylokinase Displays Surprisingly Low Mechanical Stability , Langmuir, 2017.1.31, 33(4): 1077~1083

• He CZ, Li S, Gao XQ, Xiao A, Hu CG, Hu XD, Hu XT, Li HB*, Nanoscale, 2019, Advance Article